Sepramesh - Genzyme's newest innovation for hernia repair - available June 1, 2000

From: Helen Dynda (
Tue Jun 20 13:57:02 2000

Genzyme Surgical Products is pleased to announce that SeprameshT, our newest innovation for hernia repair, will be available for purchase on June 1, 2000. To contact a local sales representative, call 1-800-261-1570.

Introducing SeprameshT SeprameshT Biosurgical Composite is the first prosthetic mesh with a temporary bioresorbable barrier that works to minimize adhesion formation between the mesh and underlying abdominal viscera.

SeprameshT Biosurgical Composite (SeprameshT) is a dual-component (absorbable and non-absorbable), sterile prosthesis designed for hernia repair. SeprameshT is constructed of a polypropylene mesh that is coated on one side with a bioresorbable coating composed of chemically modified sodium hyaluronate (HA) and carboxymethylcellulose (CMC).

The uncoated side of the mesh allows a prompt fibroblastic response through the interstices of the mesh, encouraging tissue ingrowth similar to polypropylene mesh alone and providing support for soft tissue repair. The HA/CMC side of the mesh provides a hydrophilic bioresorbable coating separating the mesh from underlying tissue and organ surfaces during the critical wound-healing period to minimize tissue attachment to the mesh. Shortly after placement, the HA/CMC coating becomes a hydrated gel that is slowly resorbed from the site of placement within 5-7 days and excreted from the body within 30 days.

SeprameshT Biosurgical Composite is available in the following sizes:

a.. 3 inch x 6 inch (7.6 cm x 15.2 cm) - Part No. SMBC-360 b.. 4 inch x 8 inch (10.2 cm x 20.3 cm) - Part No. SMBC-480 c.. 6 inch x 8 inch (15.2 cm x 20.3 cm) - Part No. SMBC-680 d.. 8 inch x 12 inch (20.3 cm x 30.5 cm) - Part No. SMBC-812 INDICATIONS SeprameshT Biosurgical Composite is indicated for use in the reconstruction of soft tissue deficiencies, such as for the repair of hernias.

CONTRAINDICATIONS In infants or children with future growth potential, SeprameshT Biosurgical Composite may not stretch significantly as the patient grows.

Do not use SeprameshT Biosurgical Composite for the reconstruction of cardiovascular defects.

For more information about SeprameshT please refer to the package insert. To order Sepramesh, or to contact a local sales representative, call 1-800-261-1570.

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