http://www.biotech-usa.com/endorp.htm The most important and exciting scientific discovery of our time was made 12 years ago at the John Hopkins University School of Medicine. Thanks to that breakthrough and the research that followed, we are on the threshold of a new age in medicine. Much of the debilitating chronic pain and depression that now afflict us may soon be nothing but an unpleasant memory.
In 1972 Dr. Candace Pert and Dr. Solomon Snyder showed that morphine (a powerful painkilling drug) fits into certain nerve cell structures in the brain like a key fits its lock. In other words, morphine can unlock previously unknown powers of the brain. But this was a puzzling discovery: Why do human brain cells have specific structures that interact with morphine? These two scientists, along with others, proposed a simple but radical explanation: The human brain must produce its own form of morphine!
WHAT ARE ENDORPHINS?
ENDORPHINS = ENDOGENOUS MORPHINE
Studies at major universities around the world have shown that the brain does in fact produce many hormone-like chemicals that bear a close functional resemblance to morphine. These morphine like chemicals are called endorphins (endogenous morphine) because they are produced by the body (are endogenous), and are similar to morphine.
MORPHINE FOR THE BRAIN?
Why does the brain make endorphins and what are they used for? With a bold leap of scientific imagination, researchers hypothesized that the endorphins might be part of a natural, built-in pain-control system.
The human body is an intricate and beautifully designed series of checks and balances. Why shouldnt we have a pain-control network to regulate pain perception?
THE MOST POWERFUL PAINKILLERS KNOWN...
Pain researchers began testing the endorphins by administering them to experimental animals and to human pain patients. The results surprised and impressed patients and researchers alike: The endorphins were much more powerful than morphine, the strongest painkiller we have. One of the endorphins, beta-endorphin, was 18 to 50 times more effective than morphine. Another endorphin, called dynorphin, was over 500 times stronger than morphine in some biological tests.
...CANT BE USED...
Are the endorphins the ultimate painkillers? Unfortunately, the answer is, "Yes and no." Using the endorphins themselves as drugs to control chronic pain is impractical, inefficient, costly, and sometimes even dangerous. But scientists refused to give up on the endorphins. There had to be a way to get them to work for us.
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