At Tue, 20 Jun 2000, Helen Dynda wrote:
> > Genzyme Surgical Products is pleased to announce that SeprameshT, our newest innovation for hernia repair, will be available for purchase on June 1, 2000. To contact a local sales representative, > call 1-800-261-1570. > >Introducing SeprameshT >SeprameshT Biosurgical Composite is the first prosthetic mesh with a temporary bioresorbable barrier that works to minimize adhesion formation between the mesh and underlying abdominal viscera. > >SeprameshT Biosurgical Composite (SeprameshT) is a dual-component (absorbable and non-absorbable), sterile prosthesis designed for hernia repair. SeprameshT is constructed of a polypropylene mesh that is coated on one side with a bioresorbable coating composed of chemically modified sodium hyaluronate (HA) and carboxymethylcellulose (CMC). > >The uncoated side of the mesh allows a prompt fibroblastic response through the interstices of the mesh, encouraging tissue ingrowth similar to polypropylene mesh alone and providing support for soft tissue repair. The HA/CMC side of the mesh provides a hydrophilic bioresorbable coating separating the mesh from underlying tissue and organ surfaces during the critical wound-healing period to minimize tissue attachment to the mesh. Shortly after placement, the HA/CMC coating becomes a hydrated gel that is slowly resorbed from the site of placement within 5-7 days and excreted from the body within 30 days. > >SeprameshT Biosurgical Composite is available in the following sizes: > > a.. 3 inch x 6 inch (7.6 cm x 15.2 cm) - Part No. SMBC-360 > b.. 4 inch x 8 inch (10.2 cm x 20.3 cm) - Part No. SMBC-480 > c.. 6 inch x 8 inch (15.2 cm x 20.3 cm) - Part No. SMBC-680 > d.. 8 inch x 12 inch (20.3 cm x 30.5 cm) - Part No. SMBC-812 >INDICATIONS >SeprameshT Biosurgical Composite is indicated for use in the reconstruction of soft tissue deficiencies, such as for the repair of hernias. > >CONTRAINDICATIONS >In infants or children with future growth potential, SeprameshT Biosurgical Composite may not stretch significantly as the patient grows. > >Do not use SeprameshT Biosurgical Composite for the reconstruction of cardiovascular defects. > >For more information about SeprameshT please refer to the package insert. To order Sepramesh, or to contact a local sales representative, call 1-800-261-1570. > >http://www.genzyme.com/sepramesh/welcome.htm