BURDEN OF ADHESIVE DISEASE: Impact on Patients and Surgeons

From: Helen Dynda (olddad66@runestone.net)
Thu Jan 18 22:53:55 2001


BURDEN OF ADHESIVE DISEASE: Impact on Patients and Surgeons

1.) The Impact on Patients: Impact of adhesions following initial surgery:

* Small bowel obstruction: Adhesive Disease accounts for 49-74% of small bowel obstructions.1

* Infertility: Adhesive Disease accounts for 15-20% of infertility cases.1

* Chronic pelvic pain: Adhesive Disease accounts for 20-50% of chronic pelvic pain cases.1

* Reduced quality of life1

* Loss of work days and productivity

* Increased risk, complexity and complications during subsequent surgery2

~ ~ ~ ~

>One study showed a 19% rate of adhesion-related bowel perforation during subsequent/secondary operations.

>Bowel perforations occur even more frequently (33%) during surgery for SBO.

>Patients with adhesion-related perforations had significantly higher postoperative complications (leaks, wound infections, hemorrhages and length of stay).

~ ~ ~ ~

2.) The Impact on Surgeons

* Increased reoperative times3

* Increased risk of enterotomy3

* Increased level of surgical complexity3

References

1 Ray NF, Denton WG, Thamer M, Henderson SC, Perry S. Abdominal adhesiolysis: inpatient care and expenditures in the U.S. in 1994. J. Am. Coll. Surg. 1998; 186(1): 1-9.

2 Van Goor H. Morbidity and mortality of inadvertent enterotomy during an adhesiotomy. British Journal of Surgery 2000; 87: 467-471.

3 Opelka F. Research update on adhesion prevention. Data presented at the 1998 ASCRS Symposium.

http://www.genzymebiosurgery.com/opage.asp?ogroup=1&olevel=4&opage== 204


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